Table 3.

Cox Proportional Hazards Model for Death among DTP Participants who initiated HAART in 2001–2012 (N=4589)

Variable	Unadjusted		Adjusted
	HR (95% CI)	p-value	HR (95% CI)	p-value
Year of initiation of ART
2001–2002	1.00 (−)	<0.001	1.00 (−)	<0.001
2003–2004	0.84(0.66, 1.06)		0.75(0.59, 0.95)
2005–2006	0.78(0.61, 1)		0.69(0.54, 0.88)
2007–2008	0.59(0.46, 0.76)		0.59(0.46, 0.76)
2009–2010	0.39(0.28, 0.53)		0.45(0.32, 0.61)
2011–2012	0.4(0.27, 0.58)		0.52(0.36, 0.77)
Age at ART Initiation	1.04(1.03, 1.04)	<0.001	1.04(1.04, 1.05)	<0.001
Sex
Female	1.22(1.01, 1.46)	0.04	1.41(1.16, 1.71)	<0.001
AIDS defining illness before ART
Yes	1.66(1.37, 2.01)	<0.001	1.29(1.05, 1.58)	0.02
Baseline VL (log10 c/mL)	1.5(1.28, 1.77)	<0.001	NA†
Baseline CD4 (per 100 cells)	0.73(0.69, 0.78)	<0.001	0.79(0.74, 0.84)	<0.001
Third drug of baseline therapy
Unboosted PI	1.00 (−)	0.26	NA†
Boosted PI	1.22(0.81, 1.85)
NNRTI	1.04(0.69, 1.59)
Other	1.27(0.67, 2.43)
History of injection drug use
No	1.00 (−)	<0.001	1.00 (−)	<0.001
Yes	2.65(2.19, 3.21)		2.74(2.25, 3.34)
Unknown	2.38(1.88, 3.01)		2.98(2.35, 3.78)

^†NA denotes variables that were not included in the adjusted model.