Table 1.
Select genes enriched or depleted in the epidermis after treatment with the JNK inhibitor.
| # | AFFYID | NAME | ABBREV | UNIGENE | FOLD CHANGE |
|---|---|---|---|---|---|
| Genes enriched | |||||
| 1 | Xl2.18730.1.S1_at | phosphoenolpyruvate carboxykinase 1 | pck1* | Xl.18730 | 14.2 |
| 2 | Xl2.33779.1.A1_at | cytochrome P450 family members | cyp2j2 cyp1a1* cyp2d6 |
Xl.34192 Xl.1220 Xl.26217 |
9.8 |
| 3 | Xl2.5475.1.S1_s_at | glutathione S-transferase pi 1 | gstp1* | Xl.54920 | 4.8 |
| 4 | Xl2.29027.1.S1_a_at | death associated protein-like 1 | dapl1-a | dapl1-a | 2.9 |
| 5 | Xl2.892.1.S1_a_at | arginase 2 | arg2-a | Xl.892 | 2.9 |
| 6 | Xl2.47079.1.S1_at | glutamate-ammonia ligase (glutamine synthase) | glul | Xl.83244 | 2.8 |
| 9 | Xl2.28670.1.S1_at | cysteine dioxygenase type 1 | cdo1 | Xl.34729 | 2.6 |
| 10 | Xl2.11739.1.S1_at | solute carrier family 25 (mitochondrial carrier) | slc25a10 | Xl.11739 | 2.5 |
| 11 | Xl2.28471.1.S1_at | aldolase B, fructose-bisphosphate | aldob | Xl.28471 | 2.4 |
| 12 | Xl2.14135.1.S1_at | aldo-keto reductase family 1, member C2 | akr1c2-b | Xl.14135 | 2.3 |
| 13 | Xl2.12180.1.S1_at | HIG1 hypoxia inducible domain family member | higd1a-a | Xl.12180 | 2.3 |
| 14 | Xl2.1717.1.S1_at | pyruvate dehydrogenase kinase, isozyme 4 | pdk4 | Xl.1717 | 2.2 |
| 15 | Xl2.21131.1.S1_at | ethanolamine-phosphate phospho-lyase | etnppl | Xl.21131 | 2.2 |
| Genes Depleted | |||||
| 1 | Xl2.1055.1.S1_at | ubiquitin conjugating enzyme E2E 1 | ube2e1 | Xl.61475 | 0.20 |
| 2 | Xl2.12198.1.A1_at | small nuclear ribonucleoprotein 70kDa (U1) | snrnp70 | Xl.5366 | 0.42 |
| 3 | Xl2.4515.1.S2_at | cold inducible RNA binding protein | cirbp-a | Xl.4515 | 0.47 |
| 4 | Xl2.24325.1.S1_at | ankyrin repeat and SOCS box containing 12 | asb12.2 | Xl.24325 | 0.48 |
| 5 | Xl2.3664.1.S2_at | heterogeneous nuclear ribonucleoprotein A2/B1 | hnrnpa2b1 | Xl.3664 | 0.50 |