Table 5.
Infliximab N = 598 | Etanercept N = 950 | Infliximab: Dose Escalation vs. No Escalation (p-value) | |||
Dose Escalation | No Escalation | Dose Escalation | No Escalation | ||
N = 346 | N = 252 | N = 172 | N = 778 | ||
Measure | Cost per patient (mean, SE), $ | ||||
RA Related Costs | $20,914.98 (631.15) | $16,713.20 (1,315.86) | $14,482.45 (519.97) | $13,865.48 (306.88) | <0.0001 |
Pharmacy: | |||||
Infliximab | $15,997.65 (413.51) | $9,999.87 (293.82) | $313.88 (175.79) | $197.56 (53.23) | <0.0001 |
Etanercept | $101.26 (45.32) | $178.18 (63.03) | $10,426.90 (254.66) | $10,099.71 (124.94) | |
Other | $1,049.00 (69.20) | $1,045.57 (145.45) | $1,089.33 (88.71) | $1,009.24 (48.61) | |
Total Pharmacy | $17,147.90 (418.81) | $11,223.62 (350.97) | $11,830.12 (292.80) | $11,306.51 (136.87) | |
Outpatient: | |||||
Management | $635.68 (53.29) | $766.75 (112.25) | $377.98 (29.58) | $382.19 (41.21) | |
Emergency Room | $13.85 (4.11) | $12.54 (6.32) | $4.72 (1.81) | $7.09 (1.76) | |
Ancillary | $1,601.47 (116.33) | $1,387.33 (118.42) | $842.11 (122.13) | $871.60 (90.63) | |
Total Outpatient | $2,251.00 (136.95) | $2,166.62 (176.82) | $1,224.81 (135.67) | $1,260.88 (120.64) | |
Hospitalization Costs | $1,516.08 (393.06) | $3,322.95 (1,191.16) | $1,427.52 (411.72) | $1,298.08 (249.13) | |
Non-RA Related Costs | $5,370.17 (536.68) | $6,104.37 (1,210.40) | $3,954.81 (415.94) | $4,177.57 (281.46) | 0.0302 |
Grand Total | $26,285.15 (1,022.19) | $22,817.56 (2,431.57) | $18,437.26 (809.69) | $18,043.04 (496.95) | <0.0001 |