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. 2016 Nov 18;2(11):e1600874. doi: 10.1126/sciadv.1600874

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Copyright © 2016, The Authors

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license, which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited.

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Fig. 7 — (A) Heat map of the differentially expressed gene profiles of nestin knockdown in TSPCs. Two samples were used for each. (B) Top 80 GO network analysis according to the ES of the GSEA of the whole genome, which shows the relationship of down-regulated ontology. The GO was enriched in the parental GO involved in the organ development, DNA metabolism, and cell cycle, presented in different colors. (C) Heat map of tendon-related gene expression values showing that most of the tendon-related genes were down-regulated after nestin knockdown. (D) GSEA results of tendon-related genes, showing a depression.