TABLE 1.

Candidate features considered for inclusion in the Bayesian belief network model

Candidate feature	Label	Description	States
Agea	AGE	Patient age, at the time of surgery	CV
Sex	SEX		Male Female
Sizea	PRIMARY SIZE CATEGORY	Size category of tumor in maximum dimension	≤5 cm 5–10 cm >10 cm
Deptha	DEPTH	Depth of primary tumor compared to investing fascia of limb	Superficial Deep
Sitea	SITE		Upper extremity Lower extremity
Subsite	SUBSITE	Extremity tumors distal to the vertical plane made by the axillary fold and horizontal plane made by the inguinal ligament were considered.	Hand Forearm Elbow Arm Axilla Shoulder Groin Hip Thigh Knee Leg Ankle Foot
Histologya	HISTOLOGY	Final histology following excision, review by 3 pathologists	MFH/HGPS Synovial Liposarcoma Leiomyosarcoma MPNST Fibrosarcoma Other
Varianta	VARIANT	Histologic variant, if applicable	Monophasic Biphasic…etc.
Presentation statusa	PRESENTATION STATUS	Oncologic procedures performed prior to referral (if any)	None Biopsy only Marginal excision Wide excision
Radiation-induced	RT INDUCED	Whether the sarcoma is considered radiation induced	Yes No
Referring zip code	FIRST 3 DIGITS ZIP	First 3 digits of patient’s home zip code at the time of referral	CV
Surgeona	SURGEON CODE	31 surgeons, listed anonymously	A-EE
Servicea	SERVICE CODE	2 surgical services	GMT Orthopaedic Surgery
Re-excisiona	RE EXCISION	Whether the patient, upon referral, required a tumor bed excision	Yes No
Procedurea	PROCEDURE	Type of procedure performed	Limb sparing Amputation
Bone invasiona	BONE INVASION		Yes No
Bone resectiona	BONE RESECTED		Yes No
Nerve invasiona	NERVE INVASION		Yes No
Nerve resectiona	NERVE RESECTED		Yes No
Vascular invasion	VASC INVASION		Yes No
Chemotherapy
Preopa	PREOP CHEMO		Yes No
Postopa	POSTOP CHEMO		Yes No
Radiotherapy
Preopa	PREOP RT		Yes No
Postopa	POSTOP RT		Yes No
Time to LRa	TIME TO LR	In months	CV None
Time to DRa	TIME TO DR	In months	CV None
Death from diseasea	DOD	Whether the patient died of disease, a reflection of disease-specific survival	Yes No

^aCandidate feature included in the final model.

CV = continuous variable; MFH/HGPS = malignant fibrous histiocytoma/high-grade pleomorphic sarcoma; MPNST = malignant peripheral nerve sheath tumor; GMT = Gastric & Mixed Tumor; LR = local recurrence; DR = distant recurrence.