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. 2017 Jan 23;135(4):352–362. doi: 10.1161/CIRCULATIONAHA.116.025253

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© 2016 The Authors.

Circulation is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial-NoDervis License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited, the use is noncommercial, and no modifications or adaptations are made.

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Figure 4. — Postprandial levels of TG (A) and ApoB48 (B) after a high-fat meal. (Left) Mean concentrations over time. (Right) Incremental area-under-the-curve (IAUC). Ten participants had blood samples just before and at 1, 2, 3, 5, and 8 hours after consuming a high-fat liquid meal providing 1237 Kcal per 2 m² body surface area from 75% fat, 10% protein, and 15% carbohydrate The data are presented as individual timepoints (mean±SE) and area under the curve above baseline (IAUC) (mean±SE) of plasma TG and apoB48 concentrations. Alirocumab had no effects on postprandial levels of TG and apoB48 compared with placebo. apoB indicates apolipoprotein B; and TG, triglycerides.