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. Author manuscript; available in PMC: 2018 Feb 20.
Published in final edited form as: Neuroscience. 2016 Dec 9;343:240–249. doi: 10.1016/j.neuroscience.2016.11.046

Figure 4. Striatal MSNs increase firing rate as LIDs develop.

Figure 4

A) Example waveforms of one MSN (red) and one FSI (blue) recorded from a single electrode. B) Clustering across peak-to-trough duration and half-peak-width identified 240 MSNs (red) and 146 FSIs (blue). C) Mean firing rate of MSNs increased following 6-OHDA lesion (Saline: sham-lesion (grey) vs 6-OHDA-lesioned in (red)) and as LIDs developed (Day 1 vs Day 13) while FSIs did not change as LIDs developed; data from 240 MSNs and 146 FSIs in 9 mice over 3 days. Error bars are mean ± SEM; (*) p<0.05.