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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Drug Alcohol Depend. 2016 Nov 24;171:70–83. doi: 10.1016/j.drugalcdep.2016.11.021

Table 7.

Multivariable Associations between Past 12-Month Marijuana Use Latent Class Membership and Age 50 Health Outcomes

%a AORb (99% CIc) p % AOR (99% CI) p

30-day respiratory health problems 30-day cognitive health problems
Non-users 16.7 (ref) 42.7 (ref)
Early Young Adult Moderate (EYAM) 17.9 0.98 (0.83, 1.16) 0.763 44.9 1.06 (0.94, 1.21) 0.211
Young Adult/Persistent Moderate (YA/PM) 20.0 1.04 (0.88, 1.23) 0.578 48.1 1.21 (1.06, 1.38) <0.001
Early Young Adult Heavy (EYAH) 17.4 0.87 (0.66, 1.15) 0.205 44.8 1.09 (0.88, 1.34) 0.316
Young Adult/Persistent Heavy (YA/PH) 23.1 1.00 (0.80, 1.24) 0.990 48.4 1.22 (1.02, 1.45) 0.004
    YA/PH vs. EYAM (ref) 1.02 (0.81, 1.27) 0.832 1.14 (0.96, 1.37) 0.052
    YA/PM vs. EYAM (ref) 1.06 (0.88, 1.28) 0.440 1.14 (0.98, 1.31) 0.025
    YA/PH vs. EYAH (ref) 1.15 (0.85, 1.55) 0.249 1.12 (0.89, 1.42) 0.214
    YA/PH vs. YA/PM (ref) 0.96 (0.77, 1.20) 0.655 1.01 (0.85, 1.20) 0.911
Overall poor physical health 12-month physical illness visits
Non-users 12.8 (ref) 49.2 (ref)
Early Young Adult Moderate 12.9 0.93 (0.77, 1.12) 0.308 49.6 1.04 (0.91, 1.17) 0.473
Young Adult/Persistent Moderate 14.6 0.98 (0.80, 1.18) 0.739 51.9 1.18 (1.04, 1.35) 0.001
Early Young Adult Heavy Users 12.7 0.86 (0.62, 1.18) 0.219 48.9 1.05 (0.85, 1.30) 0.533
Young Adult/Persistent Heavy 16.3 0.95 (0.74, 1.22) 0.604 52.0 1.29 (1.08, 1.53) <0.001
    YA/PH vs. EYAM (ref) 1.03 (0.80, 1.32) 0.803 1.24 (1.04, 1.48) 0.002
    YA/PM vs. EYAM (ref) 1.05 (0.85, 1.30) 0.552 1.14 (0.99, 1.32) 0.018
    YA/PH vs. EYAH (ref) 1.11 (0.78, 1.57) 0.447 1.22 (0.97, 1.55) 0.028
    YA/PH vs. YA/PM (ref) 0.98 (0.76, 1.25) 0.797 1.09 (0.91, 1.30) 0.228
12-month psychological visits Lifetime psychiatric problem
Non-users 7.7 (ref) 8.7 (ref)
Early Young Adult Moderate 11.0 1.53 (1.24, 1.89) <0.001 11.6 1.42 (1.15, 1.74) <0.001
Young Adult/Persistent Moderate 13.7 1.96 (1.59, 2.41) <0.001 12.9 1.59 (1.29, 1.96) <0.001
Early Young Adult Heavy Users 11.6 1.80 (1.29, 2.51) <0.001 12.5 1.64 (1.18, 2.28) <0.001
Young Adult/Persistent Heavy 11.5 1.85 (1.39, 2.46) <0.001 12.9 1.76 (1.34, 2.32) <0.001
    YA/PH vs. EYAM (ref) 1.21 (0.91, 1.60) 0.083 1.25 (0.95, 1.64) 0.038
    YA/PM vs. EYAM (ref) 1.28 (1.02, 1.59) 0.005 1.12 (0.90, 1.40) 0.187
    YA/PH vs. EYAH (ref) 1.03 (0.72, 1.48) 0.831 1.07 (0.75, 1.53) 0.609
    YA/PH vs. YA/PM (ref) 0.95 (0.72, 1.24) 0.600 1.11 (0.85, 1.45) 0.307
Lifetime alcohol problem Lifetime drug problem
Non-users 1.0 (ref) 0.5 (ref)
Early Young Adult Moderate 1.6 1.00 (0.58, 1.71) 0.999 0.9 1.64 (0.80, 3.39) 0.078
Young Adult/Persistent Moderate 3.5 1.74 (1.08, 2.80) 0.003 1.5 2.45 (1.26, 4.75) 0.001
Early Young Adult Heavy Users 3.1 1.61 (0.82, 3.15) 0.068 2.2 3.93 (1.70, 9.13) <0.001
Young Adult/Persistent Heavy 7.0 2.35 (1.40, 3.93) <0.001 5.0 7.78 (3.99,15.17) <0.001
    YA/PH vs. EYAM (ref) 2.35 (1.40, 3.93) <0.001 4.74 (2.46, 9.11) <0.001
    YA/PM vs. EYAM (ref) 1.74 (1.05, 2.86) 0.004 1.49 (0.75, 2.96) 0.133
    YA/PH vs. EYAH (ref) 1.46 (0.79, 2.70) 0.115 1.98 (0.96, 4.09) 0.016
    YA/PH vs. YA/PM (ref) 1.35 (0.89, 2.06) 0.065 3.18 (1.81, 5.57) <0.001

Notes: Ns (unweighted) for each outcome: respiratory problems = 9,636; cognitive problems = 9,631; overall physical health = 9,538; physical illness visits = 9,624; psychological problem visits = 9.620; psychiatric problem = 9,624; alcohol problem = 9,634; drug problem = 9,631. All other estimates have been weighted using attrition weights. Bold font indicates associations significant at p <.01 or stronger.

a

Unadjusted weighted percentage of each specified class reporting the listed age 50 health outcome.

b

AOR=Adjusted odds ratio; obtained from models simultaneously controlling for past 12-month marijuana use latent class membership as well as gender, race/ethnicity, parental education, religious commitment, age 18 binge drinking and cigarette use, marriage, college graduation, ages 35-45 income from welfare/unemployment, ages 35-45 cigarette use frequency, ages 35-45 alcohol use frequency, and cohort. Missing data on covariates were addressed by imputing means (for continuous measures) together with the use of missing data indicators.

c

CI=Confidence interval.