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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Transplantation. 2017 Feb;101(2):322–331. doi: 10.1097/TP.0000000000001552

Figure 6.

Figure 6

Inhibition of Btk Signaling Diminishes IR-Triggered Chemokine Programs. (A) qRT-PCR analysis of liver tissues after 6 hours of IRI. Liver tissues were evaluated for mRNA levels of selected chemokines. BTKB66 led to less expression of proinflammatory mediators CXCL1, CXCL2, and CXCL-10. * P<0.05. (B) Quantitative analysis of serum after 6 hours of IRI by multi-plex ELISA. Mouse sera were evaluated for protein levels of cytokines and chemokines. BTKB66 led to less pro-inflammatory mediators. * P<0.05, ** P < 0.005; n = 4–6/group. Means and standard deviation are shown.