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ABCA1−B/−B decreased ABCA1/Syn level and neurite/axonal outgrowth in PCNs. GW3965-treatment increased ABCA1/Syn levels and neurite/axonal outgrowth in ABCA1fl/fl-PCNs, but not in ABCA1−B/−B–PCNs after OGD; HDL attenuated ABCA1−B/−B–induced neurite/axonal outgrowth with or without hypoxic condition. A: WB image and quantitative data of WB and RT-PCR; B: Neurite-outgrowth after OGD and quantitative data; C: Axonal-outgrowth and quantitative data. *p<0.05, n=6/group.
