Figure 7.

Glial-Specific Genes Are Most Capable of Predicting Biological Age

(A–D) Analysis of the accuracy of cell-type-specific genes in predicting the biological age of UKBEC brain samples: (A) MG-specific genes (R² = 0.58), (B) AC-specific genes (R² = 0.58), (C) neuron-specific genes (R² = 0.35), (D) OLG precursor-specific genes (R² = 0.48).

In all plots, the y axis denotes the actual age and the x axis denotes the predicted age. MG, microglia; AC, astrocytes; OLG, oligodendrocytes. See Figure S4C for age association plots of endothelial, OLG precursor, and newly formed OLG cell-specific genes.