Figure 3.

Loss of JAK activity does not affect Socs44A expression. As compared with wild-type at various embryonic stages (A and B), germline clone derived embryos from hop^c111 mothers (C-H) display dramatically reduced or eliminated expression of Socs36E (C and D). Only a stripe of mesodermal staining in germ band extended embryos (D) remains at nearly normal intensity in the mutant embryos. In contrast, expression of Socs44A in trachea persists in hop^c111 germline clone-derived embryos that are unrescued (E) or paternally rescued (F). However, the trachea are morphologically altered and drastically reduced in unrescued (G) and paternally rescued (H) animals, as compared with wild-type (I), as evidenced by a trachealess enhancer trap (G-I).