Table 3.
Cell line | SAHA [µM] | G1 phase | S phase | G2 phase |
---|---|---|---|---|
RK33 | Control | 70.67 ± 0.456 | 10.22 ± 0.115 | 18.96 ± 0.567 |
0.5 | 75.55** ± 0.825 | 9.16** ± 0.245 | 15.72* ± 0.575 | |
1 | 82.17*** ± 0.855 | 6.91*** ± 0.666 | 11.16*** ± 0.219 | |
2 | 89.51*** ± 1.394 | 3.51*** ± 0.846 | 7.03*** ± 0.574 | |
RK45 | Control | 60.57 ± 0.683 | 16.30 ± 0.583 | 23.54 ± 0.286 |
0.5 | 64.11*** ± 0.171 | 13.65** ± 0.216 | 22.32* ± 0.300 | |
1 | 67.09** ± 1.225 | 11.45*** ± 0.564 | 21.65* ± 1.195 | |
2 | 71.40** ± 1.834 | 10.92*** ± 0.438 | 14.99** ± 1.447 | |
5 | 83.70*** ± 0.157 | 3.01*** ± 0.517 | 13.08*** ± 0.689 |
(*p<0.05; **p<0.01; ***p<0.001; Student's t-test, n=9 per concentration from three independent experiments).