Table 3.

Cell cycle analysis of larynx cancer cell lines treatment with SAHA.

Cell line	SAHA [µM]	G1 phase	S phase	G2 phase
RK33	Control	70.67 ± 0.456	10.22 ± 0.115	18.96 ± 0.567
	0.5	75.55** ± 0.825	9.16** ± 0.245	15.72* ± 0.575
	1	82.17*** ± 0.855	6.91*** ± 0.666	11.16*** ± 0.219
	2	89.51*** ± 1.394	3.51*** ± 0.846	7.03*** ± 0.574
RK45	Control	60.57 ± 0.683	16.30 ± 0.583	23.54 ± 0.286
	0.5	64.11*** ± 0.171	13.65** ± 0.216	22.32* ± 0.300
	1	67.09** ± 1.225	11.45*** ± 0.564	21.65* ± 1.195
	2	71.40** ± 1.834	10.92*** ± 0.438	14.99** ± 1.447
	5	83.70*** ± 0.157	3.01*** ± 0.517	13.08*** ± 0.689

(*p<0.05; **p<0.01; ***p<0.001; Student's t-test, n=9 per concentration from three independent experiments).