Table 2.
Univerate and multivariate analysis of factors associated with survival and recurrence of 168 HCCs.
| Univariate Analysis | Multivariate Analysis | Univariate Analysis | Multivariate Analysis | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | HR | 95% CI | P value | HR | 95% CI | P value | |
|
Age (≤49.0 vs. >49.0) |
0.743 | 0.490-1.125 | 0.161 | 0.951 | 0.602-1.322 | 0.534 | ||||||
|
Sex (female vs. male) |
0.864 | 0.499-1.496 | 0.602 | 1.503 | 0.891-2.537 | 0.127 | ||||||
|
Serum AFP (≤20 vs. >20ng/mL) |
1.342 | 0.869-2.074 | 0.185 | 1.383 | 0.926-2.065 | 0.113 | ||||||
|
HBsAg (negative vs. positive) |
0.857 | 0.496-1.483 | 0.582 | 0.799 | 0.470-1.356 | 0.405 | ||||||
|
Tumor encapsulation (absent vs. present) |
1.453 | 0.985-2.142 | 0.060 | 1.537 | 1.065-2.192 | 0.022* | ||||||
|
Cirrhosis (absent vs. present) |
2.013 | 1.179-3.435 | 0.010* | 2.134 | 1.231-3.701 | 0.007* | 1.011 | 0.658-1.552 | 0.961 | |||
|
Tumor size (≤5 vs. >5cm) |
1.689 | 1.131-2.522 | 0.010* | 2.266 | 1.534-3.348 | <0.001* | ||||||
|
Vascular invasion (absent vs. present) |
2.355 | 1.579-3.513 | <0.001* | 2.206 | 1.471-3.308 | <0.001* | ||||||
|
Tumor differentiation (I-II vs. III-IV) |
2.318 | 1.538-3.494 | <0.001* | 1.546 | 1.107-2.159 | 0.011* | 2.046 | 1.522-2.751 | <0.001* | 1.592 | 1.141-2.222 | 0.006* |
|
TNM stage (I-II vs. III-IV) |
2.056 | 1.349-3.133 | 0.001* | 2.734 | 1.823-4.100 | <0.001* | 2.492 | 1.016-6.117 | 0.046* | |||
|
Vascular pattern types (VETC-, VETC+ vs. VETC±) |
2.181 | 1.409-3.377 | 0.001* | 1.674 | 1.072-2.612 | 0.023* | 2.563 | 1.659-3.961 | <0.001* | 1.625 | 1.009-2.617 | 0.046* |