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. 2017 Jan 1;8(1):65–73. doi: 10.7150/jca.16739

Figure 3.

Figure 3

Overlap of Notch1, Notch2 and CSL binding sites. Number of Notch1, Notch2 and CSL binding sites and overlapping binding sites are shown. (A) Analysis of CHIP-seq data identified 598, 745 and 85 statistically significant peaks of reads for Notch1, Notch2 and CSL. Number of Notch1, Notch2 and CSL binding sites and overlapping binding sites are shown. (B) Notch1 and Notch2 only share a few target genes. The figure shows Notch1 and Notch2 target genes on chromosome 1. Only one gene is targeted by both Notch1 and Notch2 on chromosome 1. (C) Target gene distribution of CSL and Notch family proteins in chromosome 22. Notch1 and Notch2 only share one gene (SMTN) on chromosome 22. The numbers are path coefficients.