Table 1.
Comparative analysis of the anticancer effects of human tissue-derived normal MSCs in vitro and in vivo.
| Type of MSCs | Tumor propagating effect | Tumor inhibiting effect |
|---|---|---|
| Bone marrow | Acute lymphoblastic leukemia | Hepatocellular carcinoma |
| Acute myeoblastic leukemia | Pancreatic cancer | |
| Chronic lymphocytic leukemia | Glioma | |
| Lymphoma | ||
| Multiple myeloma | ||
| Breast cancer | ||
| Hepatocellular carcinoma | ||
| Colorectal cancer | ||
| Colon cancer | ||
| Prostate cancer | ||
| Renal cell carcinoma | ||
| Endometrial tumors | ||
| Glioma | ||
| Osteosarcoma | ||
| Prostate cancer | ||
| Ovarian cancer | ||
| Gastric cancer | ||
| Pancreatic cancer | ||
| Lung cancer | ||
| Oral tongue tumor | ||
| Adipose tissues | Acute lymphoblastic leukemia | Murine T-cell lymphoma |
| Acute promyelocytic leukemia | Multiple myeloma | |
| Chronic lymphocytic leukemia | Hepatic cancer | |
| Breast cancer | Colorectal adenocarcinoma | |
| Lung cancer | Prostate cancer | |
| Ovarian cancer | Glioma | |
| Prostate cancer | Melanoma | |
| Kaposi sarcoma | ||
| Melanoma tumor | ||
| Colon cancer | ||
| Prostate cancer | ||
| Endometrial tumors | ||
| Glioma | ||
| Head/neck cancer | ||
| Umbilical cord/cord Blood | Acute lymphoblastic leukemia | Acute lymphoblastic leukemia |
| Acute myeoblastic leukemia | Chronic myeloid leukemia in blast crisis | |
| Breast cancer | Acute myeoblastic leukemia | |
| Gastric epithelial cell | Burkitt's lymphoma | |
| Esophageal cancer | Multiple myeloma | |
| Mouse pancreatic cancer | Breast cancer | |
| Ovarian cancer | Hepatic cancer | |
| Cholangiocarcinoma | ||
| Bronchioloalveolar carcinoma | ||
| Prostate cancer | ||
| Bladder tumor | ||
| Ovarian carcinoma | ||
| Glioma | ||
| Esophageal cancer | ||
| Lung cancer |
Note: Distinct MSCs come from different origins and exhibit a diverse range of anticancer properties. The MSCs from bone marrow and adipose tissues mainly show tumor-propagating effects; however, MSCs from umbilical cord/cord blood mainly show tumor-inhibiting effects.