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. 2017 Jan 1;8(1):97–103. doi: 10.7150/jca.16819

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© Ivyspring International Publisher. This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) license (https://creativecommons.org/licenses/by-nc/4.0/). See http://ivyspring.com/terms for full terms and conditions.

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LINC01420 Knockdown suppressed tumor cell migration and invasion in vitro. (A) siRNAs dramatically suppressed LINC01420 expression in 5-8F cells (p < 0.001). (B and C) 5-8F cells were grown and transfected with LINC01420 siRNAs, or scramble siRNA. Twenty-four hours after transfection, cells were subjected to a Transwell assay without or with Matrigel to measure migration or invasion capacity. LINC01420 knockdown significantly inhibited 5-8F cell migration (p = 0.045) and invasion (p = 0.01).