Table 2. Characteristics of included studies of rs1344706 with schizophrenia in Chinese populations.
| Author, year | Diagnostic method | Region | Case |
control |
P-value | OR | 95(%) CI | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sample (N)1 | Male (%) | Age (mean, SD) | Sample (N) | Male (%) | Age (mean, SD) | ||||||
| Schizophrenia | |||||||||||
| O’Donovan9 | DSM-IV | Shanghai | 1034 | 55.1 | 38.8 (14.1) | 1034 | 50.5 | 30.0 (8.7) | 0.166 | 1.06 | 0.94–1.20 |
| Zhang12 | DSM-IV | Shanxi | 566 | 52.1 | 34.0 (12.8) | 574 | 57.3 | 29.1 (13.8) | 8.30E-04 | 1.32 | 1.12–1.56 |
| DSM-IV | Shanxi | 101 schizophrenia trios | 0.058 | 1.20 | 0.91–1.57 | ||||||
| Li15 | ICD-10 | Yuxi | 488 | 53.1 | 38.5 (10.4) | 694 | 53.5 | 37.1 (6.8) | 0.876 | 1.01 | 0.86–1.19 |
| DSM-IV | Kunming | 403 | 44.4 | 36.3 (8.7) | 604 | 44.4 | 36.6 (7.0) | 0.489 | 0.94 | 0.79–1.12 | |
| Yue22 | DSM-IV | Beijing | 746 | 53.1 | 34.5 (8.7) | 1599 | 52.9 | 35.8 (7.8) | NA | 1.11 | 0.96–1.29 |
| Shi23 | DSM-IV | Shanghai and Anhui | 1238 | 55.9 | 36.2 (12.4) | 2856 | 35.5 | 60.9 (12.2) | 0.250 | 1.06 | 0.96–1.16 |
| DSM-IV | Beijing and Shandong | 1578 | 69.8 | 36.9 (9.3) | 1592 | 50.3 | 30.8 (11.1) | 0.100 | 0.92 | 0.83–1.02 | |
| DSM-IV | Guangdong and Guangxi | 934 | 58.4 | 36.3 (16.6) | 2020 | 47.7 | 56.1 (13.5) | 0.420 | 0.95 | 0.85–1.07 | |
| Wei40 | DSM-IV | Guangdong | 100 | 53.0 | 26.5 (6.9) | 69 | 56.5 | 25.4 (5.7) | 0.064 | 0.66 | 0.43–1.02 |
| Chen14 | ICD-10 | Shandong | 570 | 61.5 | 28.2 (7.8) | 448 | 65.1 | 23.0 (7.0) | 0.013 | 1.25 | 1.05–1.49 |
| Liou24 | DSM-IV | Taiwan | 522 | 55.4 | 44.1 (9.1) | 806 | 47.5 | 67.6 (9.4) | 0.570 | 1.05 | 0.89–1.22 |
| Yang13 | DSM-IV | Northern China | 1024 | 51.4 | 27.3 (8.0) | 975 | 49.0 | 27.7 (8.0) | 0.087 | 1.12 | 0.98–1.27 |
| Wong16 | DSM-IV | Sichuan | 1086 | NA | NA | 1060 | NA | NA | NA | 0.91 | 0.81–1.02 |
| Wang, 2016 | DSM-IV | Jiangsu | 1284 | 63.0 | 45.8 (11.5) | 990 | 55.4 | 44.9 (10.1) | 0.497 | 0.96 | 0.85–1.08 |
| Bipolar disorder | |||||||||||
| Zhang21 | DSM-IV | Shanghai | 746 | NA | NA | 762 | NA | NA | 0.034 | 1.19 | 1.03–1.37 |
| Current study | DSM-IV | Shanghai | 528 | 39.7 | 42.2 ± 10.4 | 581 | 40.3 | 31.9 ± 11.3 | 0.028 | 1.21 | 1.02–1.43 |
Note: the studies in bold were GWASs. NA, not available; OR, odds ratio; 95% CI, 95% confidence interval.
1The N represents the number of individuals having genotyping data for rs1344706.