Figure 2.

FT-A attenuates yeast-induced increase of rectal temperature and pyrogenic cytokines in the plasma. (A)Intraperitoneal injection of FT-A significantly antagonized yeast-induced pyrexia on mice. (B) Changes of rectal temperature expressed by area under the curve after yeast-induced pyrexia (t=17 to 22). (C) PGE₂ and IL-8 levels in the serum were also detected by enzyme-linked Immunosorbent assay (ELISA). All bar graphs represent mean ± SD of 3 independent experiments. ^##P< 0.01,^### P< 0.001, significantly different from the Normal group; *P<0.05, **P< 0.01, ***P< 0.001, significantly different from the Yeast group.