Table 1.

Electrophysiological properties of cardiomyocytes differentiated from mES cells on day 5+3.

AP type	lentivirus	Vmax(V/s)	APA(mV)	APD50(ms)	APD90(ms)	n (%)
Sinus node-like	shRNA-Con	3.5±1.2	58.8±14.2	173.6±22.0	208±14.2	32
	shRNA-Rictor	2.93±0.9	17.6±14.3**	169.3±15.7	226±23.3	45
Ventricular-like	shRNA-Con	65.4±10.6	89.4±7	214.5±21.7	270±45.5	43
	shRNA-Rictor	10.6±2.0***	61.6±19***	250.7±25.8**	365.5±58.6**	14
Atrial-like	shRNA-Con	69.3±7.4	71.4±8.3	107.9±17.03	167.0±15.8	21
	shRNA-Rictor	59.1±12.4	65.3±17.1	188.6±10.9**	256.6±23.3**	41

Data were means±SD. n indicated the number of cells tested. Vmax, maximum rate of AP increase. APA, AP amplitude. APD50, AP duration measured at 50% repolarisation. APD90, AP duration measured at 90% repolarisation. **P <0.01 and ***P <0.001 compared with shRNA-Con.