Fig. 2.

Effects of PK2 on FB and KC proliferation and cytokines secretion. a. Effects of PK2 on FB and KC proliferation when they were co-cultured. b. Effects of PK2 on IL-1α production in KC. c, d. Effects of PK2 on IL-1α and IL-1β production in Raw 264.7 alone or co-cultured with FB or KC. e–g. Effects of PK2 on GM-CSF, IL-8, and IL-6 production in KC, FB, and KC co-cultured with FB by ELISA. h–l. Effects of PK2 on mRNA expression of GM-CSF, IL-8, IL-6, IL-10, and KGF in FB alone or FB co-cultured with KC by qPCR. All the bars represent the average of three independent experiments ± SD. Significant statistics difference indicated by asterisks (*, P < 0.05; **, P < 0.01).