Table 3.
Expression of calcium channels in control adrenal cortex (CA) and aldosterone producing adenoma (APA)a.
| Gène | Protein | Type | CA | APA | P value |
|---|---|---|---|---|---|
| CACNA1C | Cav1.2 | L-type | 7.182 | 21.45 | P < 0.0001 |
| CACNA1D | Cav1.3 | L-type | 2.252 | 3.684 | P = 0.0607 |
| CACNA1I | Cav3.3 | T-type | 1.864 | 1.644 | P = 0.1148 |
| CACNA1H | Cav3.2 | T-type | 1.682 | 1.651 | P = 0.6029 |
| CACNA1E | Cav2.3 | R-type | 1.441 | 3.302 | P = 0.0009 |
| CACNA1A | Cav2.1 | P/Q-type | 1.272 | 3.399 | P < 0.0001 |
| CACNA1G | Cav3.1 | T-type | 0.6967 | 0.6747 | P = 0.6130 |
| CACNA1S | Cav1.1 | L-type | 0.5508 | 0.7413 | P = 0.9235 |
| CACNA1B | Cav2.2 | N-type | 0.5397 | 0.5753 | P = 0.5948 |
| CACNA1F | Cav1.4 | L-type | 0.4809 | 0.5642 | P = 0.3467 |
a
mRNA expression was retrieved from a transcriptome studies including 123 APA and 11 CA (Boulkroun et al., 2012). P-values indicate the differences between CA and APA.