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. 2017 Jan 25;7:40989. doi: 10.1038/srep40989

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Fluorescence spectral images from dissected intestines and the attached mesentery. Images shown are from mCherry channel (red; left column) and DIR channel (green; middle column). The merged images (right column) demonstrate the best colocalization of mCherry and DIR signals (white arrow) in animals that received DIR-RGD-NP. A representative animal for each delivery system is shown; (n = 4 for soluble DIR and DIR-NP; n = 12 for DIR-RGD-NP).