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. 2017 Jan 25;7:40801. doi: 10.1038/srep40801

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Copyright © 2017, The Author(s)

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(a) M1-C forms polymers in vitro at low pH conditions as shown by negative staining electron microscopy. The width of the circular or spiral filaments is approximately 10 nm. The inset shows a close-up of some rod-like structures that associate laterally to form the filament. The scale bars are 50 nm. (b) M1-C also forms monomers at low pH conditions that produced the experimental SAXS data (red); the scattering pattern computed from the Dammin model shown in d is drawn in green. (c) Kratky plots for M1-C (red) and M1-A (blue). (d) Structural model of M1-C produced at low pH and reconstructed ab initio.