Fig. 2.

VCI in adult monkeys with surgically-induced chronic hypertension. a Arteriogram showing surgical coarctation of the thoracic aorta (arrow) in the monkey. b Delayed non-matching to sample (DNMS) scores for re-acquisition of the basic task. Y-axis: errors to criterion for control (sham-operated, black bar) and hypertensive monkeys (grey bar). c Delayed recognition span (DRS) test scores. Y-axis: group mean span, for control (black bars) and hypertensive monkeys (grey bars). d Blood pressure correlates with overall cognitive function. Y-axis: blood pressure (mmHg). X-axis: cognitive function index. The level of impairment on this index was significantly and linearly related to both systolic (black symbols, solid line; r = 0.80, P < 0.005) and diastolic blood pressure (open symbols, dashed line; r = 0.75, P < 0.005). Modified from [52] with permission