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. Author manuscript; available in PMC: 2017 Jan 25.
Published in final edited form as: Mol Imaging Biol. 2012 Feb;14(1):106–114. doi: 10.1007/s11307-010-0466-y

Fig. 5.

Fig. 5

Micro-PET and biodistribution of 64Cu-AMD3100 in lung tumors. a Representative photographs of liver and lung tumors from mice at 3 weeks after intravenous injections with either CHO-XR4 or 3LL-XR4 cells. b Micro-PET images of mice bearing lung tumors after injection of 64Cu-AMD3100, from right to left: CHO-XR4 lung tumors, coronal view; 3LL-XR4 lung tumors, sagittal view; 3LL-XR4 lung tumors, coronal view; and coronal view of mouse with 3LL-XR4 lung tumors also injected with excess unlabeled AMD3100/plerixafor. Data in a and b are from individual CHO-XR4 and 3LL-XR4 mice and are representative of three mice. c Biodistribution of 64Cu-AMD3100 in CHO-XR4 lung and liver tumors or (d) 3LL-XR4 lung tumors, and blocking with excess unlabeled AMD3100/plerixafor. Bars show means±SD. Bracketed horizontal lines indicate significantly lower percent of injected dose per gram in mice also injected with excess unlabeled AMD3100/plerixafor. Data are from two to three mice.