Table 2.

ROC area under the curve (AUC) data together with sensitivity and specificity performance for Southampton-specific striatal binding ratios (SBR) and BRASS striatal and putaminal SBR

		Calibrated			Non-calibrated
		ACSC	IRNC	FBP	ACSC	IRNC	FBP
ROC (AUC)	BRASS striatum	0.901	0.916	0.884	0.904	0.915	0.897
	BRASS putamen	0.915	0.924	0.897	0.919	0.921	0.906
	Southampton	0.876	0.866	0.876	0.874	0.866	0.874
Sensitivity	BRASS striatum	83.7	86.1	83.7	79.1	67.4	74.4
	BRASS putamen	83.7	83.7	81.4	83.7	76.7	81.4
	Southampton	90.7	76.7	67.4	65.1	67.4	60.5
Specificity	BRASS striatum	85.3	82.4	79.4	85.3	91.2	88.2
	BRASS putamen	82.4	85.3	79.4	85.3	91.2	88.2
	Southampton	82.4	82.4	82.4	88.2	88.2	88.2

The table shows the results for data with and without using a phantom calibration for iterative reconstruction with attenuation and scatter/septal penetration reconstruction (ACSC), iterative reconstruction with no corrections (IRNC) and filtered back projection reconstruction, again with no corrections (FBP). The best performance measure for each quantification technique is in bold, while the weakest is shown in italics