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Kaplan–Meier analysis of first-ever stroke (A), ischemic stroke (B), and ICH (C) according to tertiles of GDF-15. Subjects in the highest tertile of GDF-15 had lower first-ever stroke-free survival (log-rank P = 0.001), ischemic stroke-free survival (log-rank P = 0.026), and ICH-free survival (log-rank P = 0.035) in the patients with hypertension. GDF-15 = growth differentiation factor 15; ICH = intracerebral hemorrhage.
