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. 2016 Sep 30;95(39):e4906. doi: 10.1097/MD.0000000000004906

Figure 8.

Figure 8

Statins inhibit the mevalonate metabolic pathway. Statins can reduce other intermediate metabolites of the mevalonate pathway metabolic pathway except inhibition of cholesterol synthesis by inhibiting the HMG-CoA reductase, such as farnesyl pyrophosphate ester and dragon bull Quiron geraniol pyrophosphate synthesis. HMG-COA = 3-hydroxy-3-methyl glutaryl coenzyme A.