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Increase in ATP release in diabetic corneal synaptosomes. Potassium chloride stimulation enhanced ATP release of diabetic synaptosomes, in comparison to controls. NO-donor–incubated control synaptosomes, as well as glycosidase-treated diabetic synaptosomes, showed minimum ATP release on nerve stimulation by potassium chloride. DEA NONOate = diethylamine NONOate, GSNO = S-nitrosoglutathione, NO = nitric oxide.
