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. 2017 Jan 24;112(2):250–264. doi: 10.1016/j.bpj.2016.12.004

Figure 8.

Figure 8

Heavier beads promote shorter SOD1 fibrils. (A) TEM images of D90A apo-SOD1 fibrils in the presence of HDPE, borosilicate glass, and stainless steel beads. White arrows point to the short fibril fragments formed in the presence of stainless steel and borosilicate glass beads. (B) Histograms of fibril length (ntotal = 723) for each bead type. Fibril lengths were measured using cellSens software and histograms were fit with a three-parameter Gaussian distribution. The value above each histogram shows the median fibril length.