Table 3. Differentiation of MGE-derived in toto cryopreserved precursors.
Interneuron Subtypes | Hippocampus | Cortex |
---|---|---|
Parvalbumin | 31,08 ± 4,27% | 30,9 ± 4,15% |
Somatostatin | 35,93 ± 4,54% | 31,38 ± 4,32% |
Neuropeptide Y | 17,15 ± 2,50% | 19,95 ± 3,44% |
Calretinin | 10,35 ± 0,95% | 1,51 ± 0,3% |
Calbindin | 8,35 ± 0,95% | 14,45 ± 1,3% |
Thawed cells were immediately grafted into the neonatal brain (P3-5) and quantified 4 weeks after the transplantation (n = 6). Values represent percentages of double positive cells for GFP and each marker in the total population of graft-derived GFP+ cells, expressed as mean ± SEM.