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. 2017 Jan 25;12(1):e0170741. doi: 10.1371/journal.pone.0170741

Table 2. Results of ROC curve analysis of validated differentially expressed proteins.

AUC: Area Under the ROC Curve.

KNG1 AMBP APOA2 AHSG SERPINA1 HBB CRP
IPF-Control AUC 0.9325 0.9425 0.9425 0.94 0.8375 0.92 0.8825
Std. Error 0.04847 0.04532 0.03743 0.03945 0.07434 0.04549 0.06245
95% confidence interval 0.8375 to 1.028 0.8537 to 1.031 0.8691 to 1.016 0.8627 to 1.017 0.6918 to 0.9832 0.8308 to 1.009 0.7601 to 1.005
P-value < 0.0001 < 0.0001 < 0.0001 < 0.0001 0.0003 < 0.0001 < 0.0001
IPF-Sarcoidosis AUC 0.9275 0.865 0.6675 0.825 0.705 0.6275 0.7
Std. Error 0.04923 0.06445 0.08596 0.07362 0.101 0.09488 0.08315
95% confidence interval 0.8310 to 1.024 0.7387 to 0.9913 0.4990 to 0.8360 0.6807 to 0.9693 0.5070 to 0.9030 0.4415 to 0.8135 0.5370 to 0.8630
P-value < 0.0001 < 0.0001 0.0699 0.0004 0.0265 0.1677 0.0305
IPF-HP AUC 0.91 0.9025 0.6225 0.89 0.72 0.685 0.71
Std. Error 0.05443 0.05604 0.08909 0.05512 0.09681 0.09353 0.08217
95% confidence interval 0.8033 to 1.017 0.7926 to 1.012 0.4478 to 0.7972 0.7819 to 0.9981 0.5302 to 0.9098 0.5016 to 0.8684 0.5489 to 0.8711
P-value < 0.0001 < 0.0001 0.185 < 0.0001 0.0173 0.0453 0.0231