Table 2. Results of ROC curve analysis of validated differentially expressed proteins.
KNG1 | AMBP | APOA2 | AHSG | SERPINA1 | HBB | CRP | ||
---|---|---|---|---|---|---|---|---|
IPF-Control | AUC | 0.9325 | 0.9425 | 0.9425 | 0.94 | 0.8375 | 0.92 | 0.8825 |
Std. Error | 0.04847 | 0.04532 | 0.03743 | 0.03945 | 0.07434 | 0.04549 | 0.06245 | |
95% confidence interval | 0.8375 to 1.028 | 0.8537 to 1.031 | 0.8691 to 1.016 | 0.8627 to 1.017 | 0.6918 to 0.9832 | 0.8308 to 1.009 | 0.7601 to 1.005 | |
P-value | < 0.0001 | < 0.0001 | < 0.0001 | < 0.0001 | 0.0003 | < 0.0001 | < 0.0001 | |
IPF-Sarcoidosis | AUC | 0.9275 | 0.865 | 0.6675 | 0.825 | 0.705 | 0.6275 | 0.7 |
Std. Error | 0.04923 | 0.06445 | 0.08596 | 0.07362 | 0.101 | 0.09488 | 0.08315 | |
95% confidence interval | 0.8310 to 1.024 | 0.7387 to 0.9913 | 0.4990 to 0.8360 | 0.6807 to 0.9693 | 0.5070 to 0.9030 | 0.4415 to 0.8135 | 0.5370 to 0.8630 | |
P-value | < 0.0001 | < 0.0001 | 0.0699 | 0.0004 | 0.0265 | 0.1677 | 0.0305 | |
IPF-HP | AUC | 0.91 | 0.9025 | 0.6225 | 0.89 | 0.72 | 0.685 | 0.71 |
Std. Error | 0.05443 | 0.05604 | 0.08909 | 0.05512 | 0.09681 | 0.09353 | 0.08217 | |
95% confidence interval | 0.8033 to 1.017 | 0.7926 to 1.012 | 0.4478 to 0.7972 | 0.7819 to 0.9981 | 0.5302 to 0.9098 | 0.5016 to 0.8684 | 0.5489 to 0.8711 | |
P-value | < 0.0001 | < 0.0001 | 0.185 | < 0.0001 | 0.0173 | 0.0453 | 0.0231 |