Table 3.
Comparison of demographic and clinical variables during initial presentation and first recurrence among recurrence group
| Variables | At initial presentation (N=28) (%) | At first recurrence (N=28) (%) | P-valuea |
|---|---|---|---|
| Point-of-care | 0.02b | ||
| Ambulatory | 16 (57.1) | 25 (89.3) | |
| Inpatient | 12 (42.9) | 3 (10.7) | |
|
| |||
| History | 0.01b | ||
| Headache | 24 (85.7) | 14 (50.0) | 0.11 |
| Cough | 13 (46.4) | 7 (25.0) | 0.04b |
| Vomiting | 13 (46.4) | 5 (17.9) | 1.00 |
| Diarrhea | 1 (3.6) | 2 (7.1) | |
|
| |||
| nPCR diagnosis | 1.00 | ||
| P. vivax mono-infection | 22 (78.6) | 22 (78.6) | |
| Mixed P. vivax and P. falciparum | 6 (21.4) | 5 (17.9)c | |
|
| |||
| Severe malariad | 3 (10.7) | 0 | 0.24 |
|
| |||
| Antimalarial treatment | 0.07 | ||
| CQ-PQ | 22 (78.6) | 27 (96.4) | |
| ACT-PQ | 6 (21.4) | 1 (3.6) | |
a
McNemar chi-square test.
b
P-value less than 0.05 showing statistically significant differences.
c
Blood sample could not be obtained at first recurrence for DNA extraction.
d
As per the WHO’s guideline for management of severe malaria in the year 2012.