Table 3.

Location of the clusters found in the maps from the correlation of the GM volume in ε4− w.r.t. ε4+ associated with the CSF YKL-40 in the AD continuum

Group (contrast)	Distribution	Brain regions	MNI coordinates			Cluster size	Z-score
			x	y	z
AD continuum (ε4− > ε+)	Cluster 1	Cerebellum Crus L	−34	−50	−42	2473	4.50
		Cerebellum L & R
		Vermis
	Cluster 2	Fusiform R	36	−76	−8	226	3.87
		Occipital Inf R
		Lingual R
	Cluster 3	Temporal Inf R	56	−66	−18	511	3.81
		Temporal Mid R
	Cluster 4	Frontal Med Orb L	−10	52	−10	206	3.81
		Rectus R
		Frontal Med Orb R
	Cluster 5	Angular R	42	−64	36	309	3.60
		Occipital Mid R

Abbreviations: GM, gray matter; CSF, cerebrospinal fluid; AD, Alzheimer's disease.