Table 1.
Sample Characteristics, Recurrence Score (RS) Test Status and Adjusted ORs for Likelihood of 21-Gene Assay Tests in HR positive and Node Negative Breast Cancer Women, N=143
| Characteristic | Total N(%) | Yes RS N(%) | No RS N(%) | P value | Adjusted ORs 95% CI |
|---|---|---|---|---|---|
| Age Mean (SD) | 55.9(11.0) | 58.7(10.1) | 53.8(11.3) | .011 | 1.04 (1.01, 1.08)† |
| Race | |||||
| Black | 78(54.5) | 33(42.3) | 45(57.7) | .647 | 0.71 (.35, 1.45) |
| White | 65 (45.7) | 30(46.2) | 35(53.8) | ref | |
| Married/Partnered | |||||
| Yes | 71(49.3) | 32(45.1) | 39(54.9) | .809 | |
| No | 74(50.3) | 31(43.1) | 41(56.9) | ||
| Education | |||||
| ≤HS | 26(18.2) | 11(42.3) | 15(57.7) | .843 | |
| >HS | 117(81.8) | 52(44.4) | 65(55.6) | ||
| Highest Grade Completed | |||||
| ≤HS | 26(18.2) | 11(42.3) | 15(57.7) | .248 | |
| Any college | 41(28.7) | 14(34.1) | 27(65.9) | ||
| ≥College degree | 76(53.1) | 38(50) | 38(50) | ||
| Employed full-time | |||||
| Yes | 47(35.6) | 22(46.8) | 25(53.2) | .978 | |
| No | 85(64.4) | 40(47.1) | 45(52.9) | ||
| Insurance | |||||
| Private | 84(66.1) | 36(42.9) | 48(57.1) | .259 | |
| Public | 43(33.9) | 23(53.5) | 20(46.5) | ||
| Tumor Size | |||||
| <2cm | 92(66.2) | 41(44.6) | 51(55.4) | .989 | |
| ≥2 cm | 47(33.8) | 21(44.7) | 26(55.3) | ||
| Stage | |||||
| I | 86(67.2) | 42(48.8) | 44(51.2) | .902 | |
| II | 42(32.8) | 21(50) | 21(50) | ||
| Surgery | |||||
| Lumpectomy | 97(67.8) | 41(42.3) | 56(57.7) | .536 | |
| Mastectomy | 46(32.2) | 22(47.8) | 24(52.2) | ||
| Initiated Chemotherapy | |||||
| Yes | 31(21.7) | 13(41.9) | 18(58.1) | .788 | |
| No | 112(78.3) | 50(44.6) | 62(55.4) | ||
| Hormonal Therapy | |||||
| Yes | 115 (80.4) | 57 (49.6) | 58(50.4) | .005 | 3.82 (1.38, 10.57)† |
| No | 28 (19.6) | 6 (21.4) | 22(78.6) | ref | |
| Initiated radiation therapy | |||||
| Yes | 86(60.1) | 40(46.5) | 46(53.5) | .468 | |
| No | 57(39.9) | 23(40.4) | 34(59.6) | ||
| Comorbidity | |||||
| No Comorbidity | 42(29.4) | 18(42.9) | 24(57.1) | .853 | |
| One or more | 101(70.6) | 45(44.6) | 56(55.4) | ||
| BMI | |||||
| <25 Normal | 46(34.8) | 22(47.8) | 24(52.2) | .886 | |
| ≥25 Overweight/obese | 86(65.2) | 40(46.5) | 46(53.5) | ||
| Chemo-Communication | |||||
| Low | 77(53.8) | 36(46.8) | 41(53.2) | .4843 | |
| High | 66(46.2) | 27(40.9) | 39(59.1) | ||
| Chemotherapy Attitudes | |||||
| Low | 76(53.5) | 39(51.3) | 37(48.7) | .0728 | |
| High | 66(46.5) | 24(36.4) | 42(63.6) | ||
| Understanding and participation in care | |||||
| Low | 61(46.6) | 30(49.2) | 31(50.8) | .694 | |
| High | 70(53.4) | 32(45.7) | 38(54.3) | ||
| Maintaining a positive attitude | |||||
| Low | 60(46.5) | 26(43.3) | 34(56.7) | .502 | |
| High | 69(53.5) | 34(49.3) | 35(50.7) | ||
| Suspicion of mistrust | |||||
| Low | 66 (40.9) | 22(39.3) | 34(60.7) | .377 | |
| High | 81(59.1) | 38(46.9) | 43(53.1) | ||
| Religiosity | |||||
| Low | 66(50.0) | 32(48.5) | 34(51.5) | .729 | |
| High | 66(50.0) | 30(45.5) | 36(54.5) | ||
| Race-based discrimination | |||||
| Yes | 47(32.9) | 17(36.2) | 30(63.8) | .181 | |
| No | 96(67.1) | 46(47.9) | 50(52.1) | ||
†
P<.05