Table 1.

Tissue weights (as % of total body weight)

	WT-LFD n = 6	WT-WD n = 4	Pak1 KO-LFD n = 6	Pak1 KO-WD n = 6
Body weight (g)	34.7 ± 2	38.8 ± 2	33.9 ± 3	38.6 ± 1
Tissue (% body weight)
Pancreas	0.83 ± 0.07	0.80 ± 0.05	0.91 ± 0.11	0.84 ± 0.04
Spleen	0.30 ± 0.06	0.30 ± 0.04	0.32 ± 0.10	0.28 ± 0.03
Kidney	0.67 ± 0.05	0.60 ± 0.07	0.67 ± 0.08	0.59 ± 0.08
Heart	0.54 ± 0.06	0.46 ± 0.05	0.60 ± 0.13	0.47 ± 0.05
Lung	0.51 ± 0.07	0.63 ± 0.11	0.70 ± 0.07	0.48 ± 0.07
Fat	4.17 ± 0.34	5.90 ± 0.30a,b	3.85 ± 0.59	5.22 ± 0.18c,d
Intestine	1.41 ± 0.20	1.17 ± 0.07	1.26 ± 0.19	1.27 ± 0.15
Liver	5.43 ± 0.52	4.57 ± 0.14b	4.85 ± 0.31	4.60 ± 0.09d
Muscle	0.96 ± 0.05	0.73 ± 0.11	0.93 ± 0.07	0.87 ± 0.11

Data represent the average ± SEM

Weights were collected after 13 weeks of feeding the diets indicated, for determination of variables shown Statistically significant differences were detected by two-way ANOVA using a Tukey’s multiple comparison test

^aWT-WD vs Pak1 KO-LFD;

^bWT-WD vs WT-LFD;

^cPak1 KO-WD vs Pak1 KO-LFD;

^dPak1 KO-WD vs WT-LFD