Table 1.
Potential DDI findings for seven pairs of drug families
| 2 | 3 | 4 | 5 | 6 | 7 | 8 | |
|---|---|---|---|---|---|---|---|
| DDI family pair (A, B) | # of ingredients in Family A in FDB |
# of ingredients in Family B in FDB |
# of actual FDB DDIs |
# of ingredients in Family A in NDF-RT |
# of ingredients in Family A in both FDB and NDF-RT |
# of potential DDIs found in other sources |
|
| 1 | (Sulfonamides; Antidiabetics, Oral) | 6 | 8 | 48 | 52 | 4 | 93 |
| 2 | (Sulfonamides, Anticoagulants) | 22 | 6 | 132 | 52 | 15 | 21 |
| 3 | (NSAIDs, ACE inhibitors or ARBs) | 68 | 24 | 1632 | 43 | 21 | 73 |
| 4 | (NSAIDs, Loop diuretics) | 70 | 7 | 490 | 43 | 21 | 16 |
| 5 | (NSAIDs, Beta blockers) | 12 | 27 | 324 | 43 | 7 | 81 |
| 6 | (Phenothiazines, Narcotics) | 6 | 11 | 66 | 32 | 5 | 73 |
| 7 | (Benzodiazepines, Macrolide antibiotics) |
4 | 5 | 20 | 22 | 3 | 37 |
| Total: | n/a | n/a | 2712 | n/a | n/a | 394 |