Table 2.

Basic physiological and metabolic parameters of control and high-fat diet mice.

	Male		Female
	CD	HFD	CD	HFD
Leptin (ng/mL)	4.1 ± 0.9	10.2 ± 0.9*	4.7 ± 1.1	11.9 ± 1.4*
Insulin (ng/mL)	66.3 ± 17.1	512.6 ± 43.7*	59.4 ± 6.9	496.7 ± 54.5*
Cholesterol (mmol/L)	0.29 ± 0.04	0.37 ± 0.03*	0.27 ± 0.06	0.38 ± 0.04*
Triglycerides (mmol/L)	0.89 ± 0.20	0.91 ± 0.19	0.86 ± 0.38	0.87 ± 0.24
Glycemia (mg/dL)	137.0 ± 18.0	196.9 ± 13.0*	115.3 ± 21.5	179.10 ± 18.2*
Hb1AC	4.7 ± 0.1	5.6 ± 0.3*	4.5 ± 0.2	5.8 ± 0.3*
IL-6 (pg/mL)	14.2 ± 1.8	40.9 ± 10.0*	9.2 ± 3.8	48.2 ± 17.9*
TNF-α (pg/mL)	15.1 ± 1.8	47.7 ± 8.4*	18.3 ± 1.6	53.2 ± 4.9*

Data are expressed as means ± SEM.

^*P < 0.05 vs. respective lean mice. (n per group: CD male: 7; CD female: 5; HFD male: 5; HFD female: 6).