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. 2017 Jan 26;11:20. doi: 10.3389/fnins.2017.00020

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Copyright © 2017 Dalziel, Anderson, Peters, Lynch, Spencer, Dekker and Roy.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Contractile motility patterns in the isolated large intestine. Representative examples show a 10 min recording of muscle contraction from each of the four recording locations for the pre-treatment control (after 1–2 h of equilibration), over 30–60 min of treatment with: (A) Krebs buffer treatment control, (B) 1 μM prucalopride, and (C) HN019 extract (10%), and following 60 min of washout with Krebs buffer. The enlarged windows show synchronous contractions that overlap in time.