FIG. 7.
Quantification of the histological assessment of the regenerated nerve fibers three and six months after implantation. (A) Average axon diameter of regenerated myelinated nerve fibers. (B) Average diameter of the regenerated nerve fiber. (C) Average thickness of regenerated myelinated sheath. (D) Average density of regenerated myelinated nerve fibers (n = 6, *p < 0.05). In all of the assessments, no significant differences were observed between the PPY/ PDLLA and autograft. There tended to be a higher density of myelinated fibers and thicker myelin in fibers from the PPY/PDLLA group over the autograft at both three and six months. Nerves and axons in the autograft group, however, tended to have a greater than the PPY/PDLLA group at six months. (Reprinted with permission from Elsevier15.)