Table 2.

Effect of vitamin K supplementation and arterial stiffness in human subjects.

Authors	Year of publication	Follow- up	Dose of vitamin K	Study population	Results
Fulton et al. [34]	2016	6 months	Oral 100 mcg vitamin K2	Participants aged ≤70 years, with a history of vascular disease	A modest nonsignificant decrease in pulse wave velocity (PWV)
Knapen et al. [35]	2015	3 years	180 μg menaquinone	120 healthy postmenopausal women	carotid-femoral PWV and the stiffness index β decreased
Vossen et al. [36]	2015	24 months	360 microgram menaquinone-7 (MK-7)	Patients with coronary artery disease	Difference in coronary artery calcification score between MK-7 and control group