Table 1.
Comparisons of baseline characteristics between patients in high TAP and low TAP groups.
| Characteristic | All (N = 213) | TAP ≤ 112 (n = 98) | TAP > 112 (n = 115) | P value |
|---|---|---|---|---|
| Age (years) | 54.53 ± 15.62 | 57.3 ± 15.5 | 51.1 ± 15.1 | 0.008 |
| Female, n (%) | 76 (35.7%) | 35 (35.7%) | 41 (35.7%) | 0.25 |
| Diabetes, n (%) | 56 (26.3%) | 27 (27.6%) | 29 (25.2%) | 0.76 |
| Weight (Kg) | 71 ± 9.6 | 70 ± 9.5 | 69 ± 9.6 | 0.53 |
| BMI (Kg/m2) | 24.7 ± 0.9 | 24.9 ± 1.0 | 24.5 ± 1.6 | 0.83 |
| Dialysis vintage (months) | 24 (12–48) | 36 (12–60) | 36 (12–48) | 0.55 |
| Systolic Bp (mmHg) | 134 ± 21.8 | 135.5 ± 19.6 | 133.5 ± 24.4 | 0.38 |
| Diastolic Bp (mmHg) | 72.0 ± 13.73 | 70.7 ± 12.0 | 74.1 ± 13.8 | 0.86 |
| Haemoglobin (g/dL) | 10.3 ± 2.0 | 10.2 ± 1.9 | 9.9 ± 2.1 | 0.10 |
| Potassium (mmol/L) | 4.62 ± 0.8 | 4.6 ± 0.9 | 4.6 ± 0.8 | 0.55 |
| Calcium (mmol/L) | 2.25 ± 0.14 | 2.32 ± 0.30 | 2.34 ± 0.29 | 0.58 |
| Corrected calcium (mmol/L) | 2.40 ± 0.25 | 2.50 ± 0.22 | 2.50 ± 0.21 | 0.42 |
| iPTH (pg/mL) | 307 (148–656) | 246 (137–527) | 325 (152–693) | 0.09 |
| Phosphate (mmol/L) | 1.59 ± 0.6 | 1.60 ± 0.6 | 1.40 ± 0.6 | 0.07 |
| 25-OH vitamin D (ng/mL) | 21.16 ± 10.71 | 20.4 ± 8.8 | 22.2 ± 12.9 | 0.83 |
| Alkaline phosphatase (U/L) | 112 (74–163) | 74 (62–96) | 163 (130–223) | <0.001 |
| Albumin (g/L) | 31.9 ± 6.0 | 32.6 ± 5.4 | 30.3 ± 6.5 | 0.98 |
| Type of vascular access | ||||
| Arteriovenous fistula | 129 (60.6%) | 65 (66.3%) | 64 (55.7%) | 0.23 |
| Graft | 39 (18.3%) | 23 (23.5%) | 26 (22.6%) | 0.88 |
| Catheter | 45 (21.1%) | 21 (21.4%) | 24 (20.9%) | 0.97 |
| Alanine transaminase (U/L) | 21.1 ± 8.9 | 17.6 ± 8.7 | 22.9 ± 8.8 | 0.20 |
| Kt/V | 1.44 ± 0.28 | 1.4 ± 0.3 | 1.4 ± 0.2 | 0.72 |
| n PCR (g/kg/day) | 1.10 ± 0.24 | 1.02 ± 0.30 | 1.08 ± 0.27 | 0.56 |
| T. cholesterol (mmol/L) | 4.18 ± 0.91 | 4.3 ± 0.9 | 4.1 ± 0.9 | 0.14 |
| Medications | ||||
| Calcium carbonate, n (%) | 163 (76.5%) | 77 (78.6%) | 86 (74.7%) | 0.74 |
| Alfacalcidol, n (%) | 137 (64.3%) | 61 (62.2%) | 76 (66.1%) | 0.55 |
| ESA n (%) | 198 (93.0%) | 94 (95.9) | 104 (90.4%) | 0.50 |
| ESA dose (U/week) | 13373 ± 4205 | 13714 ± 4768 | 12957 ± 3457 | 0.53 |
Continuous variables are presented as means ± standard deviations or median (interquartile range) and categorical data as frequencies (percentages), BP = blood pressure, i PTH = intact parathyroid hormone, TAP = total alkaline phosphatase, ESA = erythropoietin stimulating agent, n PCR = normalized protein catabolic rate, and BMI = body mass index.