Table 3.

Twenty-five most statistically significant CpG sites that were associated with former vs. never smoker status

Probe ID	Chr	Location	Gene Symbol*	Coef†	S.E.	P	FDR
cg01940273	2	233,284,934		−0.0234	0.0013	9.6 × 10−73	1.8 × 10−68
cg25189904	1	68,299,493	GNG12	−0.0283	0.0021	3.5 × 10−40	3.3 × 10−36
cg12803068	7	45,002,919	MYO1G	0.0191	0.0017	9.3 × 10−31	5.8 × 10−27
cg19572487	17	38,476,024	RARA	−0.0159	0.0014	2.2 × 10−30	1.0 × 10−26
cg11554391	5	321,320	AHRR	−0.0091	0.0008	1.0 × 10−28	3.9 × 10−25
cg05951221	2	233,284,402		−0.0396	0.0036	1.1 × 10−27	3.2 × 10−24
cg23771366	11	86,510,998	PRSS23	−0.0167	0.0015	1.2 × 10−27	3.2 × 10−24
cg26764244	1	68,299,511	GNG12	−0.0119	0.0011	2.3 × 10−27	5.4 × 10−24
cg05575921	5	373,378	AHRR	−0.0406	0.0038	8.2 × 10−27	1.7 × 10−23
cg11660018	11	86,510,915	PRSS23	−0.0157	0.0015	4.3 × 10−26	8.1 × 10−23
cg21566642	2	233,284,661		−0.0434	0.0041	1.0 × 10−25	1.7 × 10−22
cg11902777	5	368,843	AHRR	−0.0063	0.0006	2.8 × 10−25	4.3 × 10−22
cg26850624	5	429,559	AHRR	0.0118	0.0011	3.1 × 10−25	4.4 × 10−22
cg03636183	19	17,000,585	F2RL3	−0.0267	0.0026	8.9 × 10−25	1.2 × 10−21
cg15693572	3	22,412,385		0.0190	0.0019	1.5 × 10−23	1.9 × 10−20
cg17924476	5	323,794	AHRR	0.0148	0.0016	4.0 × 10−20	4.7 × 10−17
cg12513616	5	177,370,977		−0.0072	0.0008	2.4 × 10−19	2.7 × 10−16
cg07339236	20	50,312,490	ATP9A	−0.0062	0.0007	1.4 × 10−18	1.4 × 10−15
cg06126421	6	30,720,080		−0.0365	0.0042	3.0 × 10−18	3.0 × 10−15
cg14624207	11	68,142,198	LRP5	−0.0070	0.0008	5.0 × 10−18	4.7 × 10−15
cg00706683	2	233,251,030	ECEL1P2	0.0101	0.0012	1.4 × 10−17	1.2 × 10−14
cg23351584	11	86,512,100	PRSS23	−0.0048	0.0006	7.0 × 10−17	6.0 × 10−14
cg02583484	12	54,677,008	HNRNPA1	−0.0062	0.0008	1.0 × 10−15	8.5 × 10−13
cg05302489	6	31,760,426	VARS	0.0079	0.0010	2.5 × 10−15	2.0 × 10−12
cg01442064	4	5,713,450	EVC	−0.0055	0.0007	3.3 × 10−15	2.4 × 10−12

^*CpG sites without gene names are intergenic. These are all included in all the analyses.

^†Coef stands for regression coefficients