Table 1.
Association of FBXW7 mRNA or miR-32 expression with clinicopathological data from breast cancer patients by quantitative PCR
Characteristics | N | miR-32 | FBXW7 | ||
---|---|---|---|---|---|
Relative expression level | P value | Relative expression level | P value | ||
Age (year) | |||||
≤50 | 16 | 3.84 ± 2.84 | 0.100 | 1.11 ± 1.29 | 0.147 |
>50 | 11 | 2.26 ± 1.37 | 0.49 ± 0.42 | ||
Tumor size (cm) | |||||
≤2 | 5 | 3.05 ± 0.59 | 0.969 | 0.56 ± 0.46 | 0.631 |
>2 and ≤5 | 14 | 3.31 ± 3.13 | 0.66 ± 0.71 | ||
>5 | 8 | 3.08 ± 1.94 | 1.01 ± 1.34 | ||
ER status | |||||
Negative | 7 | 4.05 ± 4.26 | 0.509 | 1.08 ± 1.48 | 0.454 |
Positive | 20 | 2.89 ± 1.45 | 0.62 ± 0.63 | ||
PR status | |||||
Negative | 7 | 1.88 ± 0.90 | 0.100 | 1.18 ± 1.42 | 0.324 |
Positive | 20 | 3.65 ± 2.66 | 0.59 ± 0.64 | ||
HER-2 status | |||||
Negative | 3 | 2.10 ± 1.41 | 0.885 | 0.38 ± 0.09 | 0.479 |
Positive | 24 | 3.22 ± 2.57 | 0.79 ± 0.96 | ||
Lymph node status | |||||
Negative | 12 | 3.82 ± 3.36 | 0.24 | 0.70 ± 1.14 | 0.817 |
Positive | 15 | 2.69 ± 1.28 | 0.78 ± 0.73 | ||
Clinical stage | |||||
I–II | 19 | 3.32 ± 2.85 | 0.695 | 0.85 ± 1.05 | 0.369 |
III–IV | 8 | 2.90 ± 1.13 | 0.49 ± 0.44 | ||
Ki-67 | |||||
Negative | 2 | 3.27 ± 1.23 | 0.965 | 0.54 ± 0.23 | 0.749 |
Positive | 25 | 3.19 ± 2.53 | 0.76 ± 0.95 |