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. Author manuscript; available in PMC: 2017 Jan 26.
Published in final edited form as: Laryngoscope. 2014 Jun 17;124(Suppl 5):S1–S12. doi: 10.1002/lary.24775

Figure 8.

Figure 8

Regeneration of hair cells after IDPN vestibulotoxicity and delivery of Ad28.gfap.atoh1. Treatment of mice with IDPN resulted in a significant reduction in both Type I (8A) and Type II (8B) hair cells while maintaining a stable population of supporting cells (8C). Administration of Ad28.gfap.atoh1 at a low dose resulted in a statistically significant recovery of both type I and type II hair cells for both the low and the high dose of vector administration. Supporting cell numbers were reduced in animals that had been treated with high dose vector (8C).