TABLE 2.
Statistical analyses of the effects of saline and drug treatments on urine output, expressed as an absolute change (g) from control
The control was the mean urine output from three sessions preceding each treatment.
Treatment | Dose (mg/kg) | Urine (Δ Control, g) | S.E.M. | Post Hoc Test (Drug versus Saline) |
---|---|---|---|---|
Saline | n/a | −0.251 | 0.115 | n/a |
CP55940 | 0.32 | 1.185 | 0.348 | t = 1.02, n.s. |
Spiradoline | 3.2 | 6.127 | 0.211 | t = 4.54, ***P < 0.0001 |
3:1 Spiradoline:CP55940 | 3.3 Spiradoline + 0.13 CP55940 | 7.658 | 1.370 | t = 5.63, ***P < 0.0001 |
1:1 Spiradoline:CP55940 | 1.1 Spiradoline + 0.13 CP55940 | 4.362 | 1.512 | t = 3.29, *P < 0.05 |
1:3 Spiradoline:CP55940 | 1.1 Spiradoline + 0.39 CP55940 | 6.813 | 0.994 | t = 5.03, ***P < 0.001 |
n.s., Not significant.