Table 2.
Survivin expression according to the pathologic parameters (n = 187)
| Parameter | Survivin expression (number of cases) |
Total | p-value | |||
|---|---|---|---|---|---|---|
| 1+ | 2+ | 3+ | 4+ | |||
| Histologic differentiation | .531 | |||||
| Well | 2 | 4 | 4 | 0 | 10 | |
| Moderate | 32 | 52 | 59 | 16 | 159 | |
| Poor | 5 | 3 | 7 | 3 | 18 | |
| Invasion depth | .267 | |||||
| T2 | 1 | 3 | 3 | 1 | 8 | |
| T3 | 36 | 52 | 60 | 16 | 164 | |
| T4 | 2 | 4 | 7 | 2 | 15 | |
| Lymph node metastasis | .815 | |||||
| N0 | 17 | 20 | 26 | 10 | 73 | |
| N1 | 13 | 25 | 27 | 5 | 70 | |
| N2 | 9 | 14 | 17 | 4 | 44 | |
| Adjuvant therapy | .297 | |||||
| Yes | 32 | 54 | 65 | 18 | 169 | |
| No | 7 | 5 | 5 | 1 | 18 | |
| CD133 IHC expression | .018 | |||||
| Negative | 18 | 14 | 18 | 3 | 53 | |
| 1+ | 11 | 12 | 15 | 6 | 44 | |
| 2+ | 3 | 16 | 12 | 5 | 36 | |
| 3+ | 7 | 17 | 25 | 5 | 54 | |
IHC, immunohistochemistry.