Table 4.

Results of the multivariate Cox regression analysis of progression-free survival

Factors	Hazard ratio (95% CI)	p-value
AURKA expression (positive vs negative)	3.944 (1.821–8.542)	<.001
Age (< 65 yr vs ≥ 65 yr)	1.453 (0.726–2.907)	.291
Lymphatic invasion (present vs absent)	1.654 (0.707–3.867)	.246
Perineural invasion (present vs absent)	2.037 (1.017–4.079)	.045
TNM stage (III vs I or II)	1.489 (0.688–3.224)	.312

CI, confidence interval; AURKA, Aurora kinase A; TNM, tumor-node-metastasis.